|
| TITLE:
| Androgens and female sexuality.
| AUTHORS:
| Davis SR
| AUTHOR AFFILIATION:
| Jean Hailes Foundation, 173
Carinish Rd, Clayton, Victoria 3168, Australia. suedavis@netlink.com.au
| SOURCE:
| J Gend Specif Med 2000
Jan-Feb;3(1):36-40.
|
| [MEDLINE record in process]
| CITATION IDS:
| PMID: 11253235 UI: 21148919
| ABSTRACT:
| An accumulating body of data
indicates that many women experience a cluster of symptoms that are
responsive to testosterone treatment and may be due to androgen
deficiency. Characteristically, affected women complain of low libido,
persistent fatigue, and diminished well-being and are found to have low
circulating bioavailable testosterone. Whether the apparent therapeutic
effects of testosterone are mediated via the androgen receptor or as a
consequence of metabolism to estrogen is not known. Despite the lack of
understanding of the mechanism(s) by which testosterone may enhance
libido, the prescription of testosterone to women in a variety of
formulations is becoming increasingly popular. This article provides an
overview of the rationale for testosterone therapy in women, offers a
broad definition of androgen deficiency in women based on the clinical
experience of the author, and outlines the currently available options and
potential risks of testosterone replacement in women.
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